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Immune system Disorders: Very rare: Anaphylactic reactions.
Anaphylactic reactions of varying degrees of severity have been observed after the administration of neuromuscular blocking agents. Very rarely, severe anaphylactic reactions have been reported in patients receiving cisatracurium in conjunction with one or more anaesthetic agents.
Cardiac Disorders: Common: Bradycardia.
Vascular Disorders: Common: Hypotension.
Uncommon: Cutaneous flushing.
Respiratory, Thoracic and Mediastinal Disorders: Uncommon: Bronchospasm.
Skin and subcutaneous tissue Disorders: Uncommon: Rash.
Musculoskeletal and connective Tissue Disorders: Very rare: Myopathy, muscle weakness.
There have been some reports of muscle weakness and/or myopathy following prolonged use of muscle relaxants in severely ill patients in the ICU. Most patients were receiving concomitant corticosteroids. These events have been reported infrequently in association with cisatracurium and a causal relationship has not been established.
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